Dualsystems Biotech AG
Dualsystems Biotech is a service provider for custom proteomics for industry and academia. We are specialized in elucidating the interaction of the living cell with extracellular ligands using the ligand-receptor capture LRC-TriCEPS™ technology. For the intracellular signaling we provide the CaptiVate Services using affinity purification/mass spectrometry analysis of protein complexes. Further, we provide Shotgun Proteomics Services for proteins / peptides (LC-MS/MS services) and stable cell line generation for human (HEK, Jurkart), mouse NIH 3T3 and chinese hamster ovary (CHO) cells.
Ligand receptor capture LRC-TriCEPS™ is a conceptually new technology to identify the targets at the cell surface of your biologics. Dualsystems offers the LRC-TriCEPS™ technology as a service for fee model to the industry and academia (CaptiRec). The technology enables the unbiased identification of cell surface targets and off-targets on the living cells without genetic manipulation. Ligand-receptor capture technology can be used for many types of orphan ligands, such as peptides, proteins, antibodies, engineered affinity binders but also for viruses.
- Extracellular proteins
- Peptide ligands
- Engineered affinity binders
Unique service workflow produces complete data set. Identify all protein partners of your bait and monitor protein interactions in response to drugs / extra-cellular stimuli and map post-translational modifications based on affinity purification using a streptavidin tag.
CaptiVate Shotgun Proteomics Services using LC-MS/MS
- Identification of protein complexes and protein interactions in mammalian cells
- Profiling of signaling pathways
- analysis of post-translational modifications
- Identify protein interactions and protein complexes
- Study protein complex dynamics
Dualsystems provides the LRC-TriCEPS™ technology al CapitRec Service in a Service for free model.