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Damaris Bausch-Fluck et al. just published a cell surface protein atlas from 41 human and 31 mouse cell types. If gives a fascinating insight in the surfaceome, where the cell interacts with its surroundings and provides targets for many pharmaceutical interventions. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121314
According to a recent comment in Nature by Andrew Bradbury, Andreas Plückthun, and co-signed by 110 other scientist protein-binding reagents (e.g. antibodies) should be defined by their sequences and produced as recombinant proteins to save money and improve reproducibility of published studies (1). Additionally, this will lead to an increased reliability of antibodies used. Already…
