Applications

Protein-protein interaction studies - Custom screening services

 

 Which custom screen best fits your needs? 

 

Custom screen

Cytosolic proteins

Protein fragments or domains

Integral membrane proteins

Membrane-associated proteins

Nuclear proteins and
acidic proteins

Self-activating proteins *

DUALhybrid screen


DUALmembrane screen

DUALhunter screen



 

 * Some proteins autonomously activate transcription in a classical yeast two-hybrid system (i.e. they are "self-activating" and can't be screened using yeast two-hybrid. The DUALhunter system offers the possibility of screening such proteins for interaction partners.

 

 

 

How does a custom screen work?

  • Send us the cDNA encoding your protein of interest
  • Select a cDNA library of your choice
  • We perform the entire screening
  • You receive binding partners for your protein of interest

 

Do you need a tailor-made cDNA library for your screen?

  • Take advantage of our custom cDNA library construction service
  • We construct DUALhybrid, DUALmembrane and DUALhunter cDNA libraries
Custom cDNA library construction  

Custom screens

DUALmembrane DUALhunter DUALhybrid

Custom services

cDNA library construction

Technologies

Split-ubiquitin DUALmembrane DUALhunter Yeast two-hybrid
© Dualsystems AG, 2007