Proteomics services
Applications
Find novel interactors for your protein of interest
Monitor protein interactions in response to drugs or extracellular stimuli
Analyze post-translational modifications
Apply CaptiVate to target deconvolution and mode of action finding
Service description
- You supply the cDNA encoding your protein of interest (the bait)
- We generate a stable cell line expressing your tagged bait
- We perform affinity purification of the bait and associated proteins
- The composition of the complex is analyzed by high-sensitivity LC-MS/MS
- You receive a list of all proteins associated with your bait
Key Benefits
- Quick - 12 weeks from design to data
- Physiological - expression of the bait close to endogenous levels
- Sensitive - optimized procedure retains transient interactions
- Specific - quantitative analysis of triplicate samples and data filtering eliminates variability and background
- Versatile - special protocols for membrane proteins available
