Specialists for ligand-receptor capture technology

LRC-TriCEPS-Video

How LRC TriCEPS™ technology works

Vulcano-Plot-on-protein-level

Example of a CaptiREC (LRC-TriCEPS)

experiment performed at Dualsystems

to identify the target receptor of

Anti-EGFR-Antibody on human

breast cancer cells (MDA-MB-231)

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Testimonials

CaptiRec Service

«The fruitful collaboration with Dualsystems

Biotech using the CaptiRec LRC-TriCEPS

technology showed that even on insect

cells receptors could be identified»

Alisson M. Gontijo, Principal Investigator at CEDOC

Centro de Estudos de Doenças Crónicas

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Testimonials

CaptiRec Service

"We have been trying to identify a receptor

that has been sought after for nearly 30

years by laboratories across the globe.

Thanks to Dualsystems service CaptiRec

(LRC-TriCEPS), we now have a strong

candidate receptor."

De'Broski R. Herbert Ph.D. Assistant Professor in Residence

University of California San Francisco (UCSF)

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Testimonials

CaptiRec Service

"Thanks to LRC-TriCEPS (CaptiRec)

technology we were able to identify a long

sought receptor of our ligand using

genetically-engineered cell lines with

the support of Dualsystems"

Fumihiko Urano,

MD, PhD Samuel E. Schechter Professor of Medicine

Washington University School of Medicine

NEW! Affinity and receptor expression

CaptiRec Services detection of extracellular cell interactions 

A conceptual novel approach for ligand-receptor capture on the living cell

TriCEPS™-based ligand-receptor capture (LRC-TriCEPS™) is a novel technology. LRC-TriCEPS™ enables the unbiased identification of cell surface receptors and off-targets on the living cells without genetic manipulation. Ligand-receptor capture technology can be used for many types of orphan ligands, such as peptides, proteins, antibodies, engineered affinity binders but also for viruses.

Orphan ligands:

  • Extracellular proteins
  • Peptide ligands
  • Antibodies
  • Engineered affinity binders
  • Viruses

Dualsystems provides full analytical Services. After the method transfer a full LRC-TriCEPS™ Kit is available.

Do you want to do functional pretests with your ligand coupled to TriCEPS™?

Ask for the pretest TriCEPS™ Kit. Here

Video Interview about CaptiRec Services, ligand-receptor capture technology (LRC-TriCEPS) on the living cell


CaptiVate Services detection of intracellular signaling on stimuli

Identification of protein complexes and protein interactions in mammalian cells

Unique service workflow produces complete data set. Identify all protein partners of your bait and monitor protein interactions in response to drugs / extra-cellular stimuli and map post-translational modifications based on affinity purification using a streptavidin tag.

Learn more about CaptiVate Services


About Dualsystems Biotech AG

Dualsystems Biotech - Swiss-QualityDualsystems Biotech is a service provider for custom proteomics for industry and academia. We are specialized in elucidating the interaction of the living cell with extracellular ligands using the ligand-receptor capture LRC-TriCEPS™ technology. For the intracellular signaling we provide the CaptiVate Services using affinity purification/mass spectrometry analysis of protein complexes. Further, we provide Shotgun Proteomics Services for proteins / peptides (LC-MS/MS services) and stable cell line generation for human (HEK, Jurkart), mouse NIH 3T3 and chinese hamster ovary (CHO) cells.

 

Get your offer now!

+41 44 738 50 00

The TriCEPS™-based ligand-receptor capture technology is now available.
Interested? Enter your details.


Video LRC
Testimonials

CaptiRec Service

"We have been trying to identify a receptor that has been sought after for nearly 30 years by laboratories across the globe. Thanks to Dualsystems service CaptiRec (LRC-TriCEPS), we now have a strong candidate receptor." index

De'Broski R. Herbert Ph.D.
Assistant Professor in Residence
University of California San Francisco (UCSF)

2015-02-17T14:27:53+00:00

De'Broski R. Herbert Ph.D.
Assistant Professor in Residence
University of California San Francisco (UCSF)

“We have been trying to identify a receptor that has been sought after for nearly 30 years by laboratories across the globe. Thanks to Dualsystems service CaptiRec (LRC-TriCEPS), we now have a strong candidate receptor.”

CaptiRec Service

"Thanks to LRC-TriCEPS (CaptiRec) technology we were able to identify a long sought receptor of our ligand using genetically-engineered cell lines with the support of Dualsystems"


Washington_University_in_St

Fumihiko Urano, MD, PhD
Samuel E. Schechter Professor of Medicine
Washington University School of Medicine

2015-02-17T14:30:12+00:00

Fumihiko Urano, MD, PhD
Samuel E. Schechter Professor of Medicine
Washington University School of Medicine

“Thanks to LRC-TriCEPS (CaptiRec) technology we were able to identify a long sought receptor of our ligand using genetically-engineered cell lines with the support of Dualsystems”

CaptiRec Service

« The fruitful collaboration with Dualsystems Biotech using the CaptiRec LRC-TriCEPS technology showed that even on insect cells receptors could be identified »

Cedoc-logo

Alisson M. Gontijo,
Principal Investigator at CEDOC
Centro de Estudos de Doenças Crónicas
2015-02-24T07:32:40+00:00
« The fruitful collaboration with Dualsystems Biotech using the CaptiRec LRC-TriCEPS technology showed that even on insect cells receptors could be identified » Alisson M. Gontijo, Principal Investigator at CEDOC Centro de Estudos de Doenças Crónicas
NEW – LRC TriCEPS™ VIDEO

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